Lithium inhibits human sperm motility in vitro.

نویسندگان

  • N T Raoof
  • R M Pearson
  • P Turner
چکیده

Lithium is a widely prescribed drug used for the treatment of bipolar affective illness. Previous reports on its effects on sperm motility and male fertility are conflicting. The effect of lithium on human sperm motility was examined in vitro using the modified transmembrane migration method. This technique takes account of the dilution of lithium that occurs during the incubation. Lithium inhibits human sperm motility in vitro in concentrations comparable with those reported to be achieved in semen after oral administration.

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عنوان ژورنال:
  • British journal of clinical pharmacology

دوره 28 6  شماره 

صفحات  -

تاریخ انتشار 1989